Researchers Tightly Control Gold Nanoparticle Size
Posted June 11, 2012 8:23 AM
From Chemical & Engineering News: Latest News:
Drug Delivery: Spheres could carry cancer drugs and reduce chemotherapy's side effects
Gold nanoparticles could improve the effectiveness of cancer drugs, many researchers think, by selectively carrying the drugs to tumors. But many synthesis methods yield particles with a broad range of sizes, which probably would not pass muster with regulators. Now researchers have developed a method for making cisplatin-loaded gold spheres with tightly controlled size distribution (Inorg. Chem., DOI: 10.1021/ic202197g).
Side effects often limit patients' doses of chemotherapy drugs. Researchers have shown in the lab that affixing a drug like cisplatin to nanoparticles allows them to target tumors selectively.