"The nucleic acids are made by joining up four kinds of nucleotide to form a polynucleotide chain. The chain provides a backbone from which four kinds of side group, known as bases, jut at regular intervals. The order of the bases, however, is not regular, and it is their precise sequence that is believed to carry the genetic message. The coding problem can thus be stated more explicitly as the problem of how the sequence of the four bases in the nucleic acid determines the sequence of the 20 amino acids in the protein. -F.H.C. Crick"
Crick shared the 1962 Nobel Prize in medicine for work he had done in 1953.