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Guru
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Implantable Prosthetic Could Help Prevent Epileptic Seizures

01/05/2012 8:09 AM

This may be of interest to some of our members:

A system that could electronically detect and prevent epileptic seizures is under development at the Massachusetts Institute of Technology (MIT).

Researchers at the US university say the system will rely on an implantable prosthetic, which will detect electrical activity associated with seizures and then use light to rapidly drive or silence key neurons in order to halt the seizure.



Read more: http://www.theengineer.co.uk/sectors/medical-and-healthcare/news/implantable-prosthetic-could-help-prevent-epileptic-seizures/1011334.article#ixzz1iaZHEUjV

Just so you know, the link was autogenerated when I c'n'p'ed. I was going to link nicely....

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Guru
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#1

Re: Implantable Prosthetic Could Help Prevent Epileptic Seizures

01/05/2012 8:51 AM

Yes, it is of interest to a long-term good friend, who has now received the hyperlink. Thanks!

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#2

Re: Implantable Prosthetic Could Help Prevent Epileptic Seizures

01/05/2012 8:51 AM

Interesting, possibly life-saving.

I have a young niece (healthy, somewhat active in sports) who began having fainting spells and small seizures after getting the second dose of Gardasil. She'd never had seizures before. Apparently a small fraction of young women who receive these injections develop seizure-like symptoms afterward. If the symptoms do not go away over time, she may need a device like this.

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Guru
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#3

Re: Implantable Prosthetic Could Help Prevent Epileptic Seizures

01/05/2012 10:40 AM

Interesting and perfectly understandable in their approach.

My read on this is that it will only help a small segment of seizure disorders, at least in its current form. This is pretty invasive and relies on the ability to stop a seizure using a few key neurons. Unfortunately, not all seizures initiate in the same exact region of the brain. Some do, but not all progress or cascade through the same set of neural networks.

Some important things to consider is that diet, exercise, and quality sleep go a long way in may patients.

Phenobarbital is usually the first drug of choice, but has its own share of undesired effects.

In extreme cases surgery to remove or isolate ischemic portions of the brain have been used. Perhaps the stimulation treatment in the linked article will help some of these cases. I have known of patients that have died due to either status epilepticus (persistent or concurrent seizures of greater than 5 minutes) or something called ictal bradycardia where the seizure causes the heart to arrest. Normally, arresting the heart will cause a blood pressure drop and stop the seizure, but in some cases the seizure does not allow the heart to restart and the patient dies.

Advances such as the linked article should be a step in the right direction to possibly curb some of these extreme conditions.

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Guru
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#4
In reply to #3

Re: Implantable Prosthetic Could Help Prevent Epileptic Seizures

01/05/2012 11:39 AM

Thanks for that explanation. Like many "old" diseases, the more we learn, the more we find that under one common heading/set of symptoms hide a plethora of disease initiators.

The one that most springs to mind is "Consumption" which was likely a catch all for several lung complaints including Cystic Fibrosis and cancer.

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#6
In reply to #3

Re: Implantable Prosthetic Could Help Prevent Epileptic Seizures

01/29/2012 7:33 AM

Thank you, AH, that is a very good contribution.

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#5

Re: Implantable Prosthetic Could Help Prevent Epileptic Seizures

01/29/2012 6:17 AM

During my biological psychology studies (1980's) of brain waves of patients with epilepsy, certain brain waves changes occurred prior to the onset of a seizure. Once this warning sign was identified, some patients were able to be trained (through meditation) to change other brain waves to inhibit a full seizure. A problem with the process was that how does the patient detect the onset of the condition without the appropriate equipment providing visual (or electrical) stimuli continually. Fortunately, dogs were trained to warn the subjects and it worked fairly well for some epileptics.

It was obvious that electronic research could some day replace the dogs and the meditation with a better process based on this (neuron activity residual) phenomena. Well done MIT!

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