Definitely possible. But from where it will suck in the air ?
Normal fans are axial flow fan. ie the air enters and leaves the fan axially. But you will require the fan to suck in air radially now and discharge axially.
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You would need a large center tube to supply input air (from between the blades) from below or above. Otherwise you will create a mild vacuum at the motor where a too small supply of air will exist. The fan blades will struggle to turn and will burn the motor out very early.
Without a STRONG central supply, this will be a wasted effort.
You certainly can. There are quite a number in use. 2 impellers are used in higher pressure (resistance) applications. For example an induced draft fan on a power plant will have a higher system resistance to overcome with a fabric filter dust collection plant in the system than say an electrostatic precipitator or none at all. Here are 1 and 2 stage fans in similar configuration but they will each have different characteristic curves.
You can mount a second impeller on the other end of your pedestal motor shaft, but you would need to have a reason for it and if you did need it you will need a larger motor.