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Inhalation Technologies for Treating Influenza

07/01/2009 4:05 PM

I'm looking for some expert engineering comments on technologies for inhalation in treatment of influenza. Eucalyptus oil inhalation is an old standard for our home care of viral infections, using the lowest-tech imaginable: a splash on a tissue placed near your pillow. I recently read up on the medical research literature on natural products for influenza, turning up some promising products which have specific activity against influenza A . I have only read the abstracts – don't have access to the papers themselves – so I'm not entirely clear about the best way – or the necessary tech – to make use of these products for home care. But it makes sense to me that, if there is an inhalation product that is antiviral, it's probably the best strategy for first-line defense against airborne infection. If you could effectively kill/deactivate the virus on your lung surfaces soon after exposure, you would enjoy the benefits of an effective natural immune response, instead of getting sick..

The eucalyptus oil which is available OTC here is a great decongestant IMHO and eucalyptus in various forms is widely accepted on the basis of its clinical use. The product we use is extremely volatile – there is no need of any special tech to disperse it into the air. Experimentally, eucalyptus is anti-inflammatory and has some specific activity against common coinfections of influenza, but assays show that it has no specific activity against influenza virus.

However, I found some very promising research on cinnamon oil inhalation for influenza (arigato) I looked in the supermarket and found and purchased a cinnamon oil product. But on sniffing, I find that it is not nearly so volatile as the eucalyptus. In fact, you might get more benefit from sniffing a warm muffin. I wonder if there is a product out there which is volatile enough to use with our low-tech approach, and having some verified cinnemaldehyde content? Would mixing the cinnamon oil with volatile eucalyptus make the available cinnemaldehyde more available for the low-tech approach? I'm very happy with the "oil on a hankie near you" approach, for our own modest means. It's no extra expense and avoids issues like contact dermatitis (for cinnamon) and greasy spots on your pillow or nasty smells when the volatile element wears off. (personal experience eucalyptus). But I'm not sure that this approach is applicable or best practice for all situations. Are other inhalation techs more effective? Are they necessary for certain products, as listed below?

I found some work done on Cranesbill polyprenols for inhalation (18 articles by the same researchers searching "geranium influenza" at PubMed - (Mnogo blagodarya). The term "polyprenols" is general and my knowledge is too small, without the full articles there's no way for me to understand whether or in what way this research might be applicable or adaptable to low-tech extraction and treatment methods. I did pick up a couple of plants at the nursery (Geranium sanguineum). But haven't done the reading yet to assess how I would produce a useful home product.

Searching Abies influenza at PubMed I found this article in an English language journal and more by the same authors in Russian publications ((Spasibo) on Abies siberica ( (that's a fir tree) polyprenols, using special inhalation technology ("ultrasonic disperser"). I have only the abstracts, don't know how volatile those "polyprenols" are, and don't have a clear idea of the tech used either.

Inhalation of simmering spruce is traditional where I live, although fir is just as common in the environment. Our firs Abies balsamea produce a lot of sweet, quite volatile and incredibly sticky/messy resin. It would be easy for me to obtain raw volatile product – in August the bark of these trees is swollen with blisters full of resin – but I don't know what I would do with it to make it convenient to inhalation use. (I don't have access to distillation equipment – but if this is the only and obvious answer, please say so. If it's really medicinally valuable, maybe the government should do it)

I have used humidifier approaches to inhalation treatment, but I don't find them ideal to our climate and circumstances. The "clammy" effect of humid environments in cold climates is less than ideal: I am more comfortable with the basic precept of keeping the patient dry and warm. Are there more sophisticated technologies that produce better treatments? What would be recommended for people with few technical resources, to take advantage of antiviral inhalation therapies available in their local flora? Your comments will be much appreciated.

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#1

Re: Inhalation Technologies for Treating Influenza

07/01/2009 9:18 PM

As I advised in your last query; 'Treating Colds and Flu', although not explicit, was the recommendation to use an antihistamine to prevent reinfection via post nasal drip. SudafedĀ® or any other effective antihistamine will do, in conjunction with Echinacea and Goldenseal, (known to be effective against both type A and B viruses). Inhalation therapy begins with Mullein, (also effective against asthma) with the addition of specific herbs, and Eucalyptus is a good choice, as it is deadly to most obnoxious critters, including bedbugs.

If you're looking for advise from 'some expert engineering' you can hold your breath for all the good it will do you. My wife and I have studied this for some 50 years between us. If you are truly in pursuit of alternative medicine, I would suggest 'The Yellow Emperors Guide to Internal Medicine', because diagnostics is is the least understood of the healing arts. And the most important.

I sometimes feel I am pissing into the wind, but there is no money in unpatentable medicine.

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#2
In reply to #1

Re: Inhalation Technologies for Treating Influenza

07/02/2009 7:37 AM

hey Tippy

I was looking for your comments on different tech for inhalation: not asking for your advice on treatment (thanks all the same).

You're right that mullein has antiviral activity against influenza, though. (there are quite a few options in the antiviral category, not only these). You say you use it for inhalation: what method? Humidifier?

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#3
In reply to #2

Re: Inhalation Technologies for Treating Influenza

07/02/2009 9:43 AM

i didn't think that there was ever any "cure" for a viral infection once it is in your system?????

I thought vaccines were the only way of stopping the virus from getting a foothold?

As to inhalation science, I beilieve the trick is to make the aerosol the correct size so that the lungs can absorb it.

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#5
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Re: Inhalation Technologies for Treating Influenza

07/02/2009 4:44 PM

"i didn't think that there was ever any "cure" for a viral infection once it is in your system?????"

You're right, vaccine is the best if you can get it. A vaccine uses dead or deactivated virus to induce a specific immune response with no risk of infection. Major problem with vaccine is that viruses mutate unexpectedly, and it takes time to make a new vaccine.

Not a "cure" but second best, if you can do it, is to keep your titre low on first exposure: kill the virus on contact. The dead virus will be processed by your immune system in the same way that a vaccine does it. Of course vaccine is better - you're certain it won't cause an infection. (Live-virus vaccines have been used in the past, but people get sick sometimes so it's not recommended.)

Although there's no "cure", there is a science to treatment of viral infections. On personal experience I agree with Gwaltney: the two keys to effective treatment are (1) an antiviral specific to the pathogen and (2) an anti-inflammatory to stop virus-activated inflammation which interferes with a rapid appropriate immune response

Natural product antivirals don't override or sidestep the immune process: they're there to kill some virus, reduce the active viral titre so your body can mount an effective immune response. The other point that Gwaltney and others make, is to start treatment right away and continue regular dosing until all symptoms subside. Again I think the point is to keep your viral titre as low as possible until your specific immune system gets the upper hand.

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#4
In reply to #2

Re: Inhalation Technologies for Treating Influenza

07/02/2009 10:16 AM

Hey Smitty

I use Mullein tea for inhalation by just putting a dish towel over my head while bent over a steaming cup. Wonderful! Strain and drink it with honey and lemon. The flowers (illegal to sell in some states) can be smoked or made into tea for anxiety or asthma and emphysema.

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