In todays mainstream cosmology, dark matter is needed to allow clumping of ordinary matter to form before the expansion of the universe makes it impossible to happen.
Writes Physicsweb (1): "In recent years there has been growing support for alternative theories of gravitation to general relativity that do away with the need for dark matter altogether. One of these, devised by Jacob Bekenstein in 2004 at the Hebrew University of Jerusalem, uses vector and scalar fields in addition to the tensor used in relativity, hence the name "TeVeS" (Tensor Vector Scalar). TeVeS has already been shown to explain galaxy dynamics without the need for dark matter. But now, building upon the numerical studies by Pedro Ferreira and colleagues performed earlier this year, Scott Dodelson and Michele Liguori from Fermilab in the US have confirmed that TeVeS can also provide such sustained plasma fluctuations." See figure: "Powering galaxy formation.

Correctly describing the "cosmic power spectrum", which quantifies the temperature anisotropies in the cosmic microwave background radiation, is one of the main challenges any alternative theory of gravitation must face. Without dark matter, the prediction of general relativity (red line) fails to match the observed data (black dots) in either shape or amplitude.
Crucially, general relativity does not give sufficient "power" at any frequency to reach the top of the graph – the threshold for the formation of any structures in the universe. Dodelson and Liguori have shown that TeVeS, a modification of general relativity, does provide the necessary power to reach this threshold. (Data taken from the Sloan Digital Sky Survey.)
Original source: Phys. Rev. Lett. 97 2006
It may a bit early to jump and shout "Eureka", because just the other day dark matter has been explicitly detected right where it should be! See NASA Announces Dark Matter (2)
Links:
(1)http://physicsweb.org/articles/news/10/12/11/1 (Free subscription required)
(2)http://cr4.globalspec.com/thread/2255.
Jorrie