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Kage
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Join Date: Jun 2010
Posts: 5

MAB Media Storage Tanks

03/05/2012 10:07 PM

I am designing multiple media storage tanks from powdered media and WFI at a concentration of 21.43 g/L therefore the storage tank needs to contain some sort of mixing apparatus. I have estimated the dimensions of the storage tanks, but need help determining the type of impeller, speed of the impeller, and power generated by the impeller in order to do so. I am using a computer program to help simulate my process and these values are necessary for it to work. I am not looking for an exact value, just a correlation or suggestion to go off of. My storage tank sizes are 50, 450, 1500, 18000 and 40000 L working volumes.
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SolarEagle
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#1

Re: MAB Media Storage Tanks

03/05/2012 11:23 PM

What is the powdered media? I assume the WFI is water for injection...What are the shapes of the tanks and dimensions?

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Kage
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#2
In reply to #1

Re: MAB Media Storage Tanks

03/05/2012 11:48 PM

The powdered media is EX-CELL CD Hydrolysate Fusion by Sigma-Aldrich and the WFI is in fact water for injection. The first tank is a cylindrical shape of 93.2 in diameter and 55.92 in height. If you could elaborate, I can calculate it for the rest of my tanks. The main problems I am having are determining the impeller speed and power generated by it.

Thanks!!
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Crabtree
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#3
In reply to #2

Re: MAB Media Storage Tanks

03/06/2012 3:17 AM

This is the sort of thing that is determined by pilot-scale trials. Just don't use those stupid British airmen as pilots.

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SolarEagle
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#4
In reply to #2

Re: MAB Media Storage Tanks

03/06/2012 7:01 AM

Biological preparations are out of my area of expertise....I do know that it is mixed gently, with a high-torque impeller , but that's about all...

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Kage
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#5
In reply to #4

Re: MAB Media Storage Tanks

03/06/2012 10:17 AM

How do you know it needs a high-torque impeller? Is there an approximate value I can find for the torque needed to mix it with?

Thanks again
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Crabtree
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#6
In reply to #5

Re: MAB Media Storage Tanks

03/06/2012 10:31 AM

Well, that's where those pilot-scale trials come in. From those you determine the agitation power needed per unit mass of material to keep the stuff in suspension, and from that you determine the agitation needed in the larger vessels.

Unless I'm missing something....

Have you phoned some agitator manufacturers about setting-up some trials yet?

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SolarEagle
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#7
In reply to #5

Re: MAB Media Storage Tanks

03/06/2012 3:30 PM

Well it has to do with the viscosity, and the amount of stress you can exert on the mixture...The only machines I've seen for this purpose were small, about the size of an oven, and had magnetically driven high torque impellers...

OK here is a link I found...

http://www.sartorius-stedim.com/magnetic-mixing

Here's some impeller designs...

http://www.haywardgordon.com/documents/HG_Impeller_Technology.pdf

Here's a source for torque requirement...

http://www.sciencedirect.com/science/article/pii/S0009250901001142

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Lapin
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#8

Re: MAB Media Storage Tanks

03/07/2012 12:11 PM

Does the media manufacturer have any specification sheets that would help? Perhaps their labs have done something similar.

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Lapin
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#9

Re: MAB Media Storage Tanks

03/07/2012 12:25 PM

Try here:

» Interested in a certain SAFC product, service, or technology? Do you have a question?
» Complete our Contact / Inquiry Form and we will quickly provide you with the information you're looking for.
» Or go to our SAFC Office Locations page for site specific addresses & phone numbers.

or here:

http://www.safcglobal.com/safc-biosciences/en-us/home/biosciences-promotions/ex-cell-cd-hydrolysate.html

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