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Alzeimer's Decline of Memory

01/14/2017 7:24 PM

At what point does memory loss come to be defined as beginning alzeimer's. The assumption is that protein chains get twisted to the point that memory loss occurs?

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#1

Re: Alzeimer's decline of Memory

01/14/2017 9:55 PM

I don't think this is the proper forum for questions such as this.

Alzheimer's Disease Fact Sheet | National Institute on Aging

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#2

Re: Alzeimer's decline of Memory

01/15/2017 12:26 AM

Heidi, long time no see.....Not all memory loss is attributable to Alzheimer's, there can be several causes...

"Everyone forgets things at some time. How often have you misplaced your car keys or forgotten the name of a person you just met?

Some degree of memory problems, as well as a modest decline in other thinking skills, is a fairly common part of aging. There's a difference, however, between normal changes in memory and the type of memory loss associated with Alzheimer's disease and related disorders. And some memory problems are the result of treatable conditions.

If you're experiencing memory problems, talk to your doctor to get a timely diagnosis and appropriate care."

For more information click on link....

http://www.mayoclinic.org/diseases-conditions/alzheimers-disease/in-depth/memory-loss/art-20046326

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#3
In reply to #2

Re: Alzeimer's decline of Memory

01/16/2017 12:01 AM

Physics, chemistry, engineers, all use handbooks. Can they also work on what degree the protein chain in the brain twists to start alzheimer's? Is there a constant? Can some kind of number be applied? Chemists use eutectic point for solid, liquid, gas say for water?

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#5
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Re: Alzeimer's decline of Memory

01/16/2017 11:28 AM

..."In the harmful pathway, beta-secretase first cleaves the APP molecule at one end of the beta-amyloid peptide, releasing sAPPβ from the cell (Figure 3). Gamma-secretase then cuts the resulting APP fragment, still tethered in the neuron’s membrane, at the other end of the beta-amyloid peptide. Following the cleavages at each end, the beta-amyloid peptide is released into the space outside the neuron and begins to stick to other beta-amyloid peptides (Figure 4). These small, soluble aggregates of two, three, four, or even up to a dozen beta-amyloid peptides are called oligomers. Specific sizes of oligomers may be responsible for reacting with receptors on neighboring cells and synapses, affecting their ability to function.

It is likely that some oligomers are cleared from the brain. Those that cannot be cleared clump together with more beta-amyloid peptides. As the process continues, oligomers grow larger, becoming entities called protofibrils and fibrils. Eventually, other proteins and cellular material are added, and these increasingly insoluble entities combine to become the well-known plaques that are characteristic of AD."...

https://www.nia.nih.gov/alzheimers/publication/part-2-what-happens-brain-ad/hallmarks-ad

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#10
In reply to #3

Re: Alzeimer's decline of Memory

02/16/2017 2:10 AM

Why waste monery on building new linear accelrators when they should discover more about the leak in brain capilaries 0(I need help on these jim dandy I-Pads) . Relate mercury placed in sluies S0 ipad needed again. I see a good picture of a cleavage of a capalary in comments. \

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#7
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Re: Alzeimer's decline of Memory

01/22/2017 1:20 AM

Amaloids sp. (losing patience, sleepy) perhaps could be absorbed by a chemical. Just like mercury can absorb gold in a dredging operation. The mercury gets distilled off leaving gold behind. Mercury works for gold. What would work with amalods sp so that the bad stuff could be thrown away, disposed of, however way you want to say it.

Doctors, BiioMech and BioMed and such have a very profound way of handling alzeimers. sp. It is too complicated.

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#9
In reply to #2

Re: Alzeimer's decline of Memory

02/12/2017 12:49 AM

For Starters; lets look into Bettelila, Sphph( can[t dread my writting)cer, AcEt, close, but good enough.(My chess games usuall take a year) )never won a game yet) Maybe capillleries, (I have a bad cough you and need to rest, take honny, lemon juice . I should know my limits. Rome was not built in a day( Wrong way Charley. Synopsis is a good one.

Just think, a manager could be hired to take care of this.

I got a PChem you know Time for medicine and alittle nap. A B, look backwrds.

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#4

Re: Alzeimer's Decline of Memory

01/16/2017 4:23 AM

I can't remember.

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#6

Re: Alzeimer's Decline of Memory

01/21/2017 7:42 PM

It is likely that some oligomers are cleared from the brain. Those that cannot be cleared clump together with more beta-amyloid peptides. As the process continues, oligomers grow larger, becoming entities called protofibrils and fibrils. Eventually, other proteins and cellular material are added, and these increasingly insoluble entities combine to become the well-known plaques that are characteristic of AD.

When a dredging sp along a river for gold; mercury is found in the sluices to collect the gold. Now; can this idea be used to collect beta-amyloid peptides in the brain. Then; perhaps the twisted protein problem can be attacked?

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#8
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Re: Alzeimer's Decline of Memory

01/23/2017 9:46 AM

So if mercury can absorb gold, is there some chemical compound, organic or inorganic, that can absorb BETA AMYLOID PEPTIDES and this mixture can be disposed?

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