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Crosslinked Polymers: Safety?

10/05/2007 12:47 PM

why are crossedlinked polyacrylimide copolymers considered safe, while polyacrylimide is considered a cumulative nurotoxin?

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#1

Re: safety?

10/05/2007 2:05 PM

I beleive it has to do with the crosslinked polymers.

Seriously, by crosslinking they do not obstruct neural pathways as would otherwise be the case.

cr3

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#2

Re: safety?

10/05/2007 3:21 PM

I did a little digging and it appears that the difference is that the cross-linked version breaks down at a slower rate than the non linked version of polyacrylamide.

The real enemy appears to be acrylamide monomer, which essentially degenerates nerve endings in a process which is called dying-back. Symptoms range from a loss of sensory feeling to pins and needles as the nerves degenerate.

Acrylamide appears to disturb the effectiveness of neurotransmitters, which is the transmission and reception interface of signals from one nerve cell to the next. Think of it as an active connector in a cable or a router for a computer network. If the neurotransmitter uptake or the receptors of the nerve ending are inhibited, signals can not pass as effectively or at the extreme, not at all.

Acrylamide also negatively impacts the function of astrocytes in the brain. Astrocytes function as maintenance for the blood-brain barrier and repair and nutrition of brain cells.

UV light is one means for polyacrylamide to breakdown to its monomer variant.

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#3
In reply to #2

Re: safety?

10/06/2007 12:25 AM

OK, so where is Polyacrylimide found, and if they start to burn do you get nerve gassed?

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#5
In reply to #2

Re: safety?

10/06/2007 9:49 PM

Acryamide is not the only monomer that shows this type of behavior. Many of the intermediates and monomers used in plastics production are highly toxic. I believe it is their high level of reactivity that makes them so.

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#4

Re: Crosslinked Polymers: Safety?

10/06/2007 6:30 AM

polyacryllmide is used in biomedical. wikopedia has a good description.

crossedlinked polyacrylimide copolymers is mostly used as "watergels" in the agricultural use. it absorbs water, swells to 400 times it size, then gives up the water slowly as the ground dries.

i am interested in using it as the only aggregate in insulating concrete. when combined with portland cement, density can get down to 15 pounds per cubic foot, perhaps even lower. makes for good R value. no structural strength. almost like styrofoam.

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#6
In reply to #4

Re: Crosslinked Polymers: Safety?

10/07/2007 2:59 AM

But insulating concrete...for which kind of applications? If this polymer typically absorbs water, electrical resistance cannot be that good.

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#7
In reply to #6

Re: Crosslinked Polymers: Safety?

10/07/2007 12:11 PM

i want to build an all concrete dome. i want everything to be done in layers, floor and dome. grancrete bottom layer (waterproof), ferrocement (strength), insulated concrete (6" to 12" thick), final layer of grancrete (waterproof and 7,000 psi strength) no styrofoam, no polyurethane, no fiberglass insulation.

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#8

Re: Crosslinked Polymers: Safety?

10/07/2007 6:00 PM

You're confusing the momnomer, acrylamide, which is a neurotoxin, with polyacrylamide, which is not toxic (in normal usage). Similarly, acrylic and methacrylic monomers, diisocyanates, and many other monomeric substances are toxic, but their polymers are not. Generally, polymers are stable in ordinary usage and their monomers are not regenerated by simple handlind.

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#9
In reply to #8

Re: Crosslinked Polymers: Safety?

10/08/2007 12:33 AM

OK, so Post-It notes use a monomer for their sticky stuff. Toxic or non-toxic? And should I stop lighting my cigars with them?

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#10
In reply to #9

Re: Crosslinked Polymers: Safety?

10/08/2007 11:32 AM

For those of us that have ever put a disposable diaper on a baby in the last 15 years, lets hope there are no long term problems.

It could help explain my teenage son however.

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#11
In reply to #9

Re: Crosslinked Polymers: Safety?

10/08/2007 12:21 PM

I heard it causes uncontrollable bouncing-_-_-_-_-_-_-!

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#12
In reply to #11

Re: Crosslinked Polymers: Safety?

10/09/2007 1:49 AM

Guess so.

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#13

Re: Crosslinked Polymers: Safety?

10/18/2007 8:49 AM

1. Uncrosslinked Polyacrylamide has some solubility in water and liquids. So it will dissolve in oils and other solvents readily. While crosslinked Polyacrylamide should not disslove in water and in most liquids.

2. Uncrosslinked Polyacrylamide will have low molecular weight species (This is called molecular weight distribution) that can be easily desorbed or diffused or contaminated

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#14
In reply to #13

Re: Crosslinked Polymers: Safety?

11/23/2007 6:24 AM

Uncrosslinked polyacrylamide does not easily dissolve in most mineral oils to any appreciable level. Indeed, two phase water in oil polymerisation (acrylamide in water) has been used as an industrial method for producing pearl like polyacrylamide beads.

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