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Temperature to Cool a Fluid in a Silicon Tube

04/26/2009 7:03 PM

Hi group, I hope you all are fine.

I need to cool a fluid, cell culture serum, very similar to water, flowing at 0.12 cm3/seg in a silicon tube (0.5 mm inner diameter,1 mm width of walls). The fluid is at room temperature of 28ºC, the required temperature in the fluid is 20ºC.

The silicon tube is housed in a aluminuim heat sink that is freezed by a Peltier.

Can anybody help me with equations to calculate the required temperature in the heat sink to cool the flowing fluid at 20ºC?

thanks!

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Guru
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#1

Re: Temperature to Cool a Fluid in a Silicon Tube

04/27/2009 11:16 PM

Why don't you just do a test run with your fluid into a small reservoir with a temp probe and adjust your Peltier current until you arrive at the required temperature. This will be 100% accurate and no calculations. Also you could do this with various room temperatures and draw up a graph, this would give you a range for temperature adjustments against power to the cooling device.

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#2
In reply to #1

Re: Temperature to Cool a Fluid in a Silicon Tube

04/27/2009 11:28 PM

Dear Garth,

Thanks for you interest, but is not possible to 'touch' the fluid, is cell culture media, is sterile and the circuit is all sterile too, is not possible to create a reservoir or open the circuit to test the temperature in the fluid. So the best way seems to me that is the analyitics.

The graph is not a bad idea!,

Please do not hesitate to ask eme any question that you may have,

Esteban.

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Guru
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#3
In reply to #2

Re: Temperature to Cool a Fluid in a Silicon Tube

04/27/2009 11:55 PM

I did not except you to use the test batch for it normal purpose it is a throw away , unless is to expensive to do this, then use a sterile substitute fluid .

You would not need to use a temp probe in a reservoir for your normal operation as it would be as you say a closed circuit and sterile.

Another thought occurred to me in that when you are calibrating your refrigeration unit run your tubing through a permanent circular temperature probe and note the readings on this and compare to your test temperature readings .This will give you a temperature readout during operation which can be cross referenced so that it will give you a good indication of your process temperature assuming your flow rates remain constant.

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#4

Re: Temperature to Cool a Fluid in a Silicon Tube

04/28/2009 4:00 AM

Just thinking allowed.

You said that the serum is very similar to water. What about a "twin" control tube with water (which you can put a thermocouple in) flowing at the same rate.

The whole equipment would need to be designed to be exactly symmetrical. You would need to establish that the control "water" does have the same specific heat capacity as the serum.

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#5

Re: Temperature to Cool a Fluid in a Silicon Tube

04/28/2009 7:58 AM

The heat transfer problem can be easily solved. However, the solution will be for non-equilibrium conditions; that is, if the flow rate changes, fluid properties change, etc., the temperature will change. I would run the fluid through a temperature controlled bath at 20 deg.C. That way, as long as the tube was sufficiently long, the fluid would always exit at the bath temperature. By the way, is your tube silicon, or silicone?

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#6
In reply to #5

Re: Temperature to Cool a Fluid in a Silicon Tube

05/16/2009 10:55 PM

Thanks Welderman,

the tube is silicone

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#7
In reply to #6

Re: Temperature to Cool a Fluid in a Silicon Tube

05/17/2009 10:39 PM

By the way, is this a homework?

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