Engineering News Blog

Engineering News

Latest news of interest to engineers. Sourced from GlobalSpec's Engineering News

Previous in Blog: Vuvuzela vs Sound Engineer: Has the World Cup Stadium Horn Met Its Match?   Next in Blog: New Science GCSE Papers Rejected
Close
Close
Close
3 comments
Rate Comments: Nested

Plastic Antibodies Fight Toxins

Posted June 16, 2010 8:36 AM

From Technology Review RSS Feeds:

Polymers that mimic the body's natural defenses could be a new class of inexpensive therapeutics. For the first time, researchers have shown that a nonbiological molecule called a plastic antibody can work just like a natural antibody. In animal tests, the plastic particles bind to and neutralize a toxin found in bee stings; the toxin and antibody are then cleared to the liver, the same path taken by natural antibodies. Researchers are now developing plastic antibodies for a wider range of disease targets in hopes of broadening the availability of antibody therapies, which are currently very expensive.

Reply

Interested in this topic? By joining CR4 you can "subscribe" to
this discussion and receive notification when new comments are added.
Guru
Popular Science - Weaponology - New Member United Kingdom - Member - New Member

Join Date: May 2007
Location: Harlow England
Posts: 16512
Good Answers: 670
#1

Re: Plastic Antibodies Fight Toxins

06/16/2010 10:53 AM

Hmmm yes...and what do they do to the liver?
Del

__________________
health warning: These posts may contain traces of nut.
Reply
Anonymous Poster
#2
In reply to #1

Re: Plastic Antibodies Fight Toxins

06/16/2010 1:33 PM

Hmmm. Maybe they can use the resulting plastic "scaffolding" that'll clutter up your current liver to grow your new liver around?

Reply
Guru
Hobbies - CNC - New Member Popular Science - Biology - New Member Hobbies - Musician - New Member

Join Date: Dec 2008
Location: Canada
Posts: 3523
Good Answers: 146
#3

Re: Plastic Antibodies Fight Toxins

06/16/2010 9:31 PM

The antibody therapies are a double edged sword - there is a risk of adverse immune reactions, but in the past the adverse reactions have been caused by animal proteins that were present in the product - because it was produced in animals. There's a chance that the plastic antibodies might actually be a better choice, with lower risk as well as lower cost. I'm sure they will be doing lots of testing to make sure of it.

Antibodies are also manufactured for laboratory work - for tests such as Western Blot for example. They are quite important for biochemistry research, and the cost is significant. For these uses, I would expect that plastic antibodies are immediately applicable at no risk to anybody. The use of rabbits and other small animals as a production facility for antibodies - most probably involving some suffering on their part - would therefore be no longer necessary. Kudos to the new technology!

__________________
incus opella
Reply
Reply to Blog Entry 3 comments
Copy to Clipboard

Users who posted comments:

Anonymous Poster (1); artsmith (1); user-deleted-1105 (1)

Previous in Blog: Vuvuzela vs Sound Engineer: Has the World Cup Stadium Horn Met Its Match?   Next in Blog: New Science GCSE Papers Rejected

Advertisement