From Science 2.0:
Doctors have used drugs to induce general anesthesia in patients
undergoing surgery since a medical doctor became a legitimate profession
in the mid-1800s. But little has been known about how these drugs
create such a profound loss of consciousness. We don't understand why
aspirin works either, but it does. Yet the search for answers about the
brain is ongoing.
Anesthesiologists now rely on a monitoring system that takes
electroencephalogram (EEG) information and combines it into a single
number between zero and 100. However, that index actually obscures the
information that would be most useful, according to a new study that
tracked brain activity in human volunteers over a two-hour period as
they lost and regained consciousness, researchers from MIT and
Massachusetts General Hospital have identified distinctive brain
patterns associated with different stages of general anesthesia.
"When anesthesiologists are taking care of someone in the operating
room, they can use the information in this article to make sure that
someone is unconscious, and they can have a specific idea of when the
person may be regaining consciousness," says senior author Emery Brown,
an MIT professor of brain and cognitive sciences and health sciences and
technology and an anesthesiologist at MGH.
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