The defining characteristic of human beings with regards to other animals from an evolutionary standpoint is the size of our Cerebral Cortex. The cerebral cortex is the folded outer layer of the brain where planning, memories, and abstract thought are believed to originate.
Scientists compared the genomes of Humans, Chimpanzees, and other mammals in order to identify the genes that have been most actively changing. The researchers found that two overlapping genes, one of which is active in nerve cells and important in the developement of the cerebral cortex, have been greatly altered in humans even with respect to our evolutionary neighbor the chimpanzee.
The research sheds light on the developement of human brain functions and is consistent with the fact that our current brain size is three times larger than our predecessors. Take a look at the article below.
http://www.newscientist.com/article/dn9767-fastest evolving-human-gene-linked-to-brain-boost.html