If the environment is saltwater/marine, place the board in a sized box and pot it (fill with waterproof material and let dry). If the environment is not extremely harsh, there are clear plastic sprays that work great. If occasional humidity (even rain) is an issue, several coats of this spray will work.
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An obstacle is something you see when you take your eyes off the goal.
You probably don't need Parylene, but it will give the best coverage because it's vacuum deposited and it is recognized as a conformal coating.
I'd suggest that you look at moisture vapor transmission rates of the various materials, if moisture protection is the goal.
BTW,all these coatings allow some moisture to pass through them.
Tell us what your environment is. Temp cycle/maximum humidity/and vibration amplitude(if you want the coating to attach/stake the components to the board)
If your customer specs it, you need to use it. It's expensive and very difficult to de-mask after coating. In case it matters to you, Parylene is a good UV filter, compared to the other coatings.
What's the maximum temperature the device will see.
From what I have seen previously, we usually try to protect the environment from PCBs (polychlorinated biphenyls). But then I guess PCBs were used to protect electrical components from the environment....
There's a hole in the bucket, dear Liza....
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In vino veritas; in cervisia carmen; in aqua E. coli.