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This is my definition of a calorie.
Unfortunately, calories are really
a unit of energy. In nutrition, they refer to energy consumption through
eating and drinking, as well as energy usage through physical activity. But
they also refer to anything that contains energy, such as coal.
Humans need calories to survive, however how many
calories you need depends on a number of factors, including your general
health, physical activity demands, sex, weight, height, and shape. The average
daily consumption for a man should be somewhere around 2,700, and 2,200 for
women. But again, this number is different for everybody. Watch a video on what 200 calories looks like.

Today, every packaged food has a nutrition label listing
the number of calories in a serving of the product. But since everybody has a
different and complex digestion system most of these calories are incorrect
because they are based on a system of averages that ignore how an individual
responds to the food.
A recent
study reveals that current calorie counts do not consider that how many
calories an individual extracts from food, it depends on which species they
eat, how the food is prepared, the bacteria present in their gut, and how much
energy is used to digest different foods.
For example, vegetables vary greatly in their
digestibility. Humans are able to heat the stems, leaves, and roots of hundreds
of different plants. Within a single vegetable there are many ways to change
the amount of calories it has. Older plants tend to have studier cell walls
leading them to have fewer calories than weak or degraded plant material.
Cooking quickly ruptures cells in certain plants like spinach, but water
chestnuts are much more resistant to the effects of cooking. 
Click the image to watch the video
"When cell walls
hold strong, foods hoard their precious calories and pass through our body
intact (think corn)."
Food labels also do not always consider the structure of
different foods. It takes as much as five times more energy to digest proteins
than fats because our enzymes must unravel the tightly wound strings of amino
acids in proteins. Other foods, such as honey, are processed so quickly that
they break down right in our stomach and pass into the bloodstream.
Lastly, even if two people ate the same amount of food,
prepared the same way, they would extract a different amount of calories. This
is because there are different types and levels of bacteria in everyone's
stomach and these bacteria are responsible for the rate at which food is
processed in the digestion system. Many modern diets include food that is easy
to digest and process. This means that the population of gut microbes that
evolve to digest the more fibrous matter might be diminishing.
Calorie counts on nutrition labels will never be perfect
but scientists are working on making them more accurate. But it all comes down
to what to buy at the grocery store and living a healthy lifestyle. According
to the article, "Merely
counting calories based on food labels is an overly simplistic approach to
eating a healthy diet -- one that does not necessarily improve our health, even
if it helps us lose weight. Instead we should think more carefully about the
energy we get from our food in the context of human biology. Processed foods
are so easily digested in the stomach and intestines that they give us a lot of
energy for very little work. In contrast, veggies, nuts and whole grains make
us sweat for our calories, generally offer far more vitamins and nutrients than
processed items, and keep our gut bacteria happy. So it would be logical for
people who want to eat healthier and cut calories to favor whole and raw foods
over highly processed foods."
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