Biomedical Engineering Blog

Biomedical Engineering

The Biomedical Engineering blog is the place for conversation and discussion about topics related to engineering principles of the medical field. Here, you'll find everything from discussions about emerging medical technologies to advances in medical research. The blog's owner, Chelsey H, is a graduate of Rensselaer Polytechnic Institute (RPI) with a degree in Biomedical Engineering.

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Reverse Paralysis

Posted November 02, 2014 12:00 AM by Chelsey H

There is now hope for the 2.5 million paralyzed people in the world. An Anglo-Polish medical team at the University College of London allowed a man with a severed spinal cord to recover the ability to walk. The firefighter was paralyzed from the neck down in a knife attack. A revolutionary implant of regenerative cells has repaired the spinal cord, restoring sensation and muscle control to his legs. The technique was put into practice by surgeons in Wroclaw, Poland.

This represents the first-ever instance where a complete spinal paralysis has been reversed. The therapy uses specialist human cells which repair damage to nasal nerves to enable spinal nerve fibers to re-grow and bridge a severed cord. The harvested cells, known as olfactory ensheathing cells (OECs), were implanted into an 8mm gap in the spinal cord of the patient. The cells were found in the olfactory bulb. This part of the brain processes smell and the cells here are constantly regenerating. The OEC implants slowly restored the nerve fiber connections between both sides of the injury, returning feeling and then movement to the patient's legs.

Six months after the procedure, the patient was able to report pain from a pressure sore on his right hip - the first time he had felt sensation in his lower body since he became paralyzed. Ten months after the surgery he was able to walk with the aid of braces and a walk frame. Nineteen months after surgery, he was able to tell the direction of movement of his feet in tests with up to 85% accuracy and could tell the difference between movement of his toes and his whole foot.

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The group is now looking to raise more money to fund surgery in Poland for the next round of patients to test and refine the implant technique over the next five years. This is an important first step in finding a cure for paralysis.

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Guru

Join Date: Aug 2008
Location: England & Ireland
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#1

Re: Reverse Paralysis

11/02/2014 5:40 PM

A fantastic breakthrough. Let's hope this becomes a routine medical practice in the future.

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Power-User

Join Date: Sep 2011
Posts: 164
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#2

Re: Reverse Paralysis

11/03/2014 12:55 AM

Nice to see them finding away around using stem cells outright I'd say. But if I remember right, this patient's spinal cord was not completely severed or something.

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Participant

Join Date: Apr 2010
Location: Lagos, Nigeria
Posts: 1
#3

Re: Reverse Paralysis

11/03/2014 8:59 AM

what an amazing breakthrough! Giving hope to the paralized

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