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Super Glue Injection for Muscles and Tissue!

08/27/2009 10:33 PM

Is another tissue injection technology a bad idea?

Should super glue be used to spot fuse tissue to a desirable hold instead of Botox putty?

Could super glue injections stop swelling?

Would a glue be available that has an appropriate expiry scheme?

Is there something we should all know about this; eg. it will never meet the charity patient and have an effect on humanity or other humanitarian causes?

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#1

Re: Super glue injection for muscles and tissue!

08/27/2009 11:11 PM

No.

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#4
In reply to #1

Re: Super glue injection for muscles and tissue!

08/28/2009 3:20 AM

Ever Lynch! :)

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#2

Re: Super glue injection for muscles and tissue!

08/28/2009 12:19 AM

Possibly. Medical uses for cyanoacrylate have been around for a while, and new specific specialised uses (such as bone repair) are being looked into.

http://www.google.co.nz/search?hl=en&source=hp&q=super+glue+medical&meta=&aq=f&oq=

Could super glue injections stop swelling?

I seriously doubt it. DONT TRY THIS AT HOME KIDS!

Would a glue be available that has an appropriate expiry scheme?

Ever looked at the expiry date of cyanoacrylate glue?

Is there something we should all know about this; eg. it will never meet the charity patient and have an effect on humanity or other humanitarian causes?

Cannot answer because I don't know what you are talking about.

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#6
In reply to #2

Re: Super glue injection for muscles and tissue!

08/28/2009 3:30 AM

Could super glue injections stop swelling?

I seriously doubt it. DONT TRY THIS AT HOME KIDS!

I think SOMETIMES it's best to actually just go ahead and try it! (preferrably using a bundle of common technique wisdoms and the idea of minimized harm, especially to humans.)

But maybe a set up of tissue swelling in dead meat can be simulated on a ham or two; like a tatoo'ist or a special effects trainee!

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#3

Re: Super glue injection for muscles and tissue!

08/28/2009 1:09 AM

The tortoise tried it to its own demise.

Forget about it unless you have some positive, sustainable, safe , . . . . idea in mind.

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#5
In reply to #3

Re: Super glue injection for muscles and tissue!

08/28/2009 3:24 AM

I had an idea about some kind of micro insertion method that is at a dosage level so sparse that the working environment doesn't even notice it is enhanced or just removes it if it's somehow seperated (eg it's expiry through being discarded).

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#7

Re: Super Glue Injection for Muscles and Tissue!

08/28/2009 7:55 AM

There are serious MEDICAL researchers looking at the uses of super-glues. It can be dangerous, even fatal, work. Quit mucking about with things you aren't qualified to work with. You're going to hurt yourself or others.

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#11
In reply to #7

Re: Super Glue Injection for Muscles and Tissue!

08/29/2009 3:06 AM

Your a writer here which demands a slight reader uptake! Ok if I was to try it, it would not be pre medical reseacher testing or any oath breaking method. But if I had the opportunity to test it on harmless tissue; I would! And if I had money, I'd form my own research company. If I had access to any form of enlightenment, I would proceed! "Why choose to discuss it openly?" is because I would never hide that intention or capability from the human species!

And in a round conclusion; I have started considering superglue composites that allow lines of superglue to be etched into tissue as support but have a breakdown capability due to the composite slice being activated by the desired breakdown condition, such as a doctor using activation of an rf tag in the composite slice linking tissue adhering and retaining glues. The other idea of a dipersal system seems like a longer term research investment.

The really big discussion question I would ask is do you know if this sounds feasible to present to a qualified bio engineering think tank or research group. What do you think I need to develop beyond the 'bleeding obvious' route to take in engineering efforts that meets an industry application standard that attracts investment?

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#12
In reply to #11

Re: Super Glue Injection for Muscles and Tissue!

08/29/2009 9:03 PM

Brett Johnston:

Until you have a basic understanding of biology and physiology, and a good grasp of what has already been done (and properly tested) in the bioengineering of medical adhesives, your dream of research or financing is never going to happen. You will not get anywhere, trying to test your ideas on a ham or anything else.

Go study biology if you want to do bioengineering. A "qualified bio engineering think tank or research group" wouldn't waste time on you, because you don't understand the basics, you don't have a grasp of the terminology, research design etc. Go read that good search that Jack of All Trades brought up for you. Find the scientists working on this. Get their published papers and read how research is properly done. Find the people who are doing research that interests you, and work towards becoming a student with those professionals.

There are no shortcuts to success in the field of bioengineering. Study. Work hard.

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#14
In reply to #12

Re: Super Glue Injection for Muscles and Tissue!

08/30/2009 7:56 AM

You made a huge assumption and I like reading medical journals with a grasp. I'm not overcomplicating your life but you definitely suggested mine should be! Bill Gates recently selected his form of investment by forming a foundation; do you believe all founders need to be qualified or rather just grasp who is qualified to process the desired requirements? All I have requested is engineering discussion of a tissue retention product not much more except I revealed why I have an interest. Because I know money buys the quality of the research but you need to be heading along a path to actually achieving a truly desirable goal; hence question "is it a good idea to create another product like this?".

Possible gains, possible cons, possible alternatives, possible ability to micro suture; nothing more, nothing snarky or narky!

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#16
In reply to #14

Re: Super Glue Injection for Muscles and Tissue!

08/30/2009 7:29 PM

Brett, honey, you are not going to get money from Bill Gates just because he has no knowledge of biology. Don't kid yourself that you have a grasp of medical journals because anyone who does can tell that you don't. No assumptions required.

I like ideas, I like ideas people who push the envelope. But your ideas here are so out of whack in this post they have no value. Testing inflammation response on a ham??? You're way out of your depth in biology and bioengineering.

There are no gods on this forum, strictly human. Anyone can post in their pajamas or drunk, or plain ignorant, and then we might have to live with the history of our "bad day" mistakes. Nobody wants to "complicate your life". Since we're human, we're also forgiving. But we all also have to be mature enough to admit our errors, not ride them around like a hobby-horse.

The people who are incapable of admitting when they made a mistake or speculated on something out of their depth, are in a category that doesn't belong on CR4. That attitude won't get you anywhere. Nobody is going to pat your back here, for defending your pajama-drunk-or-ignorant errors.

I invite you to show your maturity if you want to reply to this post by acknowledging you overstepped your limits. We'll have a laugh and talk about it another day. Otherwise, ignore it, sleep it off, and do yourself better next time. Not for me, for yourself buddy.

Rest assured, you're not complicating my life.

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#18
In reply to #16

Re: Super Glue Injection for Muscles and Tissue!

08/30/2009 9:46 PM

You used a bush wack story to sell your post! Maybe it is your profession to do so but speaking in real terms your the slob; get a clue the world moves on by experiment and practice not demands of legitimacy.

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#19
In reply to #16

Re: Super Glue Injection for Muscles and Tissue!

08/31/2009 4:45 AM

Overcomplicated expectations writer please meet a simple persons efforts; http://www.workingpitbull.com/images/wound2.jpg

and yet you insist your assumption isn't off target.

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#8

Re: Super Glue Injection for Muscles and Tissue!

08/28/2009 11:03 AM

i have heard of people and i have use super glue to use as a bandied for a cut/slash. is it ok to use or harmfully. because it does work but does it poisons you.

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#9
In reply to #8

Re: Super Glue Injection for Muscles and Tissue!

08/28/2009 11:20 AM

There are medical grades for use in human tissue, but, I have also used the tube at hand to close wounds. Like most things, it probably has to do with the dose.

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#10
In reply to #9

Re: Super Glue Injection for Muscles and Tissue!

08/29/2009 2:08 AM

Works great on paper cuts!

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#13

Re: Super Glue Injection for Muscles and Tissue!

08/29/2009 11:28 PM

Should super glue be used to spot fuse tissue to a desirable hold instead of Botox putty?

LOL You would need a whole new form of "Super Glue" Permeable to cellular function and flexible yet strong. Loss of collagen connective tissue is the problem. Replacing it with something that could conceivable shatter when distressed is a bad idea.

Treat the cause not the symptom. Less money but more ethical.

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#15

Re: Super Glue Injection for Muscles and Tissue!

08/30/2009 10:32 AM

After going back and looking at your past history, I can only conclude that you are of such a remarkably high intelligence that we mere mortals, aliens, cats, dogs, gremlins, squirrels and all others here are incapable of understanding what the hell you are talking about.

I'm sure you understand perfectly, but just can't make the rest of the world get it.

Does kay williams understand you?

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#17
In reply to #15

Re: Super Glue Injection for Muscles and Tissue!

08/30/2009 9:40 PM

I'm apparently your impressionable Lynch case! Cats, dogs understand me because they are trained to repsond to humans; but the enticements I offer are not always acceptable or correct. I always have to think hard about what the hell I'm on about because I don't use prescription life in great excess!

But back to topic; you should have been great at discussing real product options for tissue adhesives from the adhesives perspective, I feel let down because you wont stop your "Lynch style" derangement. But maybe I pegged you as all (engineering)encompassing far too early! :( (Even just a slight mention about how micro, insertion methods are getting in standard engineering, because bioengineering personalities generally can't speak english ''on topic anymore and don't need to!)

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#20

Re: Super Glue Injection for Muscles and Tissue!

08/31/2009 10:28 PM

In reply to myself as a self help! Calcium carbonate is the preferred stitching material for creating structurally hardened matrix to fix tissue to and the idea of a composite with modern adhesives and fills has become standard research. http://www.science24.com/paper/15740

But the reversal of the idea, to choose a section or path within tissue to have a structural element binding such as cartilage but only as a temporary casting or tissue resetting element seems undervalued as a faster engineered technique already available due to previous developments in technology.

(I don't think I went to a different reality with that answer!)

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#21

Re: Super Glue Injection for Muscles and Tissue!

09/09/2009 4:18 PM

I read somewhere that superglue was issued in GI's first aid kits during the Viet Nam era, and works quite well to close wounds so long as there is not alot of flexing of the skin, such as around joints. My wife informs me that they use it in medicine today because it does not leave near the mess as sutures or staples. In an emergency, I would not hesitate to use it to close a wound, but some of the other ideas?? Forget it. Use the Botox for cosmetic treatments.

Bill

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#22

Re: Super Glue Injection for Muscles and Tissue!

10/10/2009 2:55 AM

Cyanoacrylates have been used in various clinical situations like arteriovenous malformations.

http://www.ncbi.nlm.nih.gov/pubmed/12006271

We had ourselves developed a compound for this that did reach controlled clinical trials. Took us ages and spent a lot to follow the due processes that accompany such biomdeical research that included invitro evaluation, detailed toxicology, animal trials, ethics committee clearance following WHO guidelines post Helsinki convention on human experimentation and ending with controlled clinical trials.. There was not enough market and the product is in abeyance.

Of course one can go on with invitro tests to evaluate the fitness for intended purpose.

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