French Researcher Posts Successful COVID-19 Drug Trial

This sounds very hopeful. *****

We still need to wait for a more "clinical" trial(s) with control groups and the like to see if the results can be duplicated. I haven't heard of any one or any other organization that is trying to replicate this.

https://sci-hub.si/https://www.sciencedirect.com/science/article/pii/S0166354220301145

https://www.cnbc.com/2020/03/19/coronavirus-treatment-trump-directs-fda-to-examine-whether-malaria-drug-can-be-used.html

Hello, Has any clinic or Health Centers tried Fresh Juice of Aloe Vera (Barbadensis Miller) on patients?

apparently it cured someone in Cameroon

he took the juice twice daily after meals.

Is this the guy?

https://www.cookingwithbooks.net/2014/04/diy-aloe-vera-juice.html

Naturally medical Experts would never agree, their dividends in pharmaceutical industries would crash.

just as the chief WHO took took many days to declare a pandemic!!!

^{but instead was using diplomacy}

Well if you get the virus you can request this as your treatment of choice and report first hand information instead of some rumor you heard someplace...peace be with you

I have about 60 plants and take fresh juice every morning, most probably I won’t be affected more than a day. Auto immune!!

Oops...!

...."Here's why: Non-decolorized, whole-leaf aloe extract contains a chemical called aloin, which has been shown to cause cancer in rats. There's one major caveat here, though: The study found aloin causes cancer only when ingested. ... To be totally clear, there is no evidence that aloe applied to the skin can causes cancer.Mar 2, 2018"...

https://www.allure.com/story/aloe-vera-skin-care-products-proposition-65-california

I have been taking that for 15 years now. My mother 83 got a cervix cancer 5 years ago , she had chemiotherapy that radiotherapy parallel to that Every morning I have given her fresh aloe jus (aloin drained and washed) with honey and lemon, SHE DID NOT LOSE A SINGLE HAIR !!!!! now in 2020 there no trace of cancer cells.

..."Doctors can choose from more than 100 different chemo drugs, used in many combinations, to treat specific types of cancer and related diseases. All of these medications and drug combinations come with their own unique set of side effects, which can vary from person to person. Some patients report only relatively minor side effects that last a short time during chemo treatment, while others may have more serious complications. But these side effects have nothing to do with whether a treatment is working.

A number of chemo drugs, for example, don’t cause hair loss because they are better able to target cancer cells – not healthy cells."...

https://blog.dana-farber.org/insight/2014/05/is-chemo-working-if-i-dont-lose-my-hair/

I was just sharing an experience which I have lived and done at home.

Aloe (Barbadensis miller) is known world wide.

That's fine, believe what you want...I use aloe vera topically as do others.....

Any way CAUTION :-

All mushroom �� are not edible

all fish �� are not edible

There are 200 Varieties of Aloe Vera

only one Identified as Aloe Barbadensis Miller is the one. Its flowers are yellow.

Hello and caution.

Autoimmune means that your immune system is not "normal" and thus could totally disregard this virus rather than heavily suppress it. You could even be at higher risk than the general population.

Heck, the virus might kick your auto-immune (read self immune) system into attacking your own body itself in addition to what the virus does. For instance one autoimmune response following viral attacks is for the immune system to attack the pancreas, thus rendering you to be type 1 diabetic.

Read also about Lupus, Sjogrens and similar autoimmune diseases where the immune system in response to (typically) a viral infection selects particular organs in the body to attack.

By all means stay fit and healthy, but also take the necessary precautions to avoid infection so that you don't face those other risks.

https://www.reuters.com/article/us-health-coronavirus-usa-treatments/two-generic-drugs-being-tested-in-u-s-in-race-to-find-coronavirus-treatments-idUSKBN2161QQ

ADMIN note: post redacted

This post has been revised to eliminate politic commentary.

-----------------------------------------------------------------------------------------------------

In May 2018, a biodefense preparedness adviser warned that a flu pandemic was the country’s No. 1 health security threat, and the U.S. was not prepared.

“We know that it cannot be stopped at the border,” Luciana Borio, director of medical and biodefense preparedness at the National Security Council, said at a symposium that day.

There STILL are NO TEST KITS in MANY states! Sick people cannot get tested.

The feds have told states they are on their own for respirators, etc.

Coronavirus Outbreak: A Cascade of Warnings, Heard but Unheeded

Government exercises, including one last year, made clear that the U.S. was not ready for a pandemic like the coronavirus.

I don't have a country to run....vetting and crosschecking information takes time, you can't make decisions effecting millions of lives without all the facts...I believe Pres Trump is responding as fast as is possible under the circumstances....this isn't the time for reckless behavior...

So I get censored for one of my "political" comments, but this, and other conservative members have free rein on politics, here and elsewhere.

If Admin is going to censor, do it consistently!

The amount of propaganda far outweighs and actual factual content of these propaganda spreaders.

People are dying due to incompetence.

One of your political posts?... you’re the Grand PoBah of Political Polluters posters here.

And Why do you always start with me,... you know i don’t tolerate it and I spank, I mean discipline.

You, your cohorts The Legion of Hate, initiate and than crossed the line too often... I’m sure if you cry enough,... I will be silenced also,... not so much I crossed the line, but just to shut your crying flapper.

and btw,

here’s a benchmark of incompetence... And you were silent.

And CORVID-19 is more contagious...

an excerpt;

The 2009 H1N1 pandemic originated in the United States before spreading around the world, according to the U.S. Centers for Disease Control and Prevention (CDC). A later study suggested it was first diagnosed in humans in Mexico. The CDC estimated that from April 12, 2009 to April 10, 2010, there were 60.8 million H1N1 cases, with 274,304 hospitalizations and 12,469 deaths in the U.S. alone. They also estimate that worldwide, 151,700 to 575,400 people died from (H1N1)pdm09 during the first year. Unusually, about 80% of the deaths were in people younger than 65 years of age.

lyn, good thing I didn’t erase the memes about you, because you’re so predictable, I can reuse them.

Not fact,... but your Opinion is noted.

I realize the difficulty you have with watching a video through it’s entirety and making a knowledgeable opinion, and since you need it more then me, I’ll be happy to do it for you as well as your cohorts... this time.

and do you also need for me to dig up how Trump mobilized industry and specialist also for you?

like the above link, it is readily available for you to do yourself. That way, you can have a better and more informed opinion.

Some people don't want the facts to get in the way of a good story.

After a bit of time we get this

https://www.medrxiv.org/content/10.1101/2020.04.16.20065920v2

for crying out loud,... French Researcher Posts Successful COVID-19 Drug Trial. And that’s what you got out of this...

You’re begining to sound like Biden.... in January Trump put in a travel ban with China et al to combat this Kung Flu before it was cool.

and then you think this was a small thing, and he didn’t do enough?.. And on top of this, he’s running a country, and all that goes with it.

you never disappoint, are you doing this on purpose? You are, aren’t you?

China's been putting out papers on chloroquine trials since late February
.
https://www.ncbi.nlm.nih.gov/pubmed/32075365

This is not a trial, it's just a single paper on recommendations arrived at by consensus opinion with no results recorded....no scientific value, no data....

Chloroquine or its combination with some other drug(s) will eventually work finally, I think.

Welcome to Fantasy Land!

Sounds like a lot of you and your cohorts are hoping more for an epidemic/pandemic under Trump, then a cure or vaccine under Trump no matter where it comes from. I expect no less from you.

as far as your link from trumps Biodefense advisor, More then likely he gave the best info/intel possible at the time. Just like N1H1 was not a threat before it became on.

Like you, this is my opinion, I hope I didn't offend anyone,... but I’m sure I did.

It really unfortunate that it’s cherry picked, and extremely hard to let this past.

you failed to mention, how it was uncovered...

“ That scenario, code-named “Crimson Contagion” and imagining an influenza pandemic, way simulated by the Trump administration’s Department of Health and Human Services in a series of exercises that ran from last January to August.”

it was this Administration that found out, departments were underperforming. And instead of business as usual in Washing DC by promoting the non-performers or creating yet another department, this is the reason why departments that were non-performing were disbanded where a more effective department is put in place.

As it should be.

the positive is it had to be done, the negative was the timing which you’re falsely taking advantage of and becoming part of the problem.

you, like your cohorts will burn your own village for your agenda and then blame the maker of the matches you used.

We heard it today - that is those who were paying attention.

You need to be kept in check,... don’t you....

here a great example of bloviating....

no, China has been testing chloroquine since late February
.
https://www.ncbi.nlm.nih.gov/pubmed/32075365

Double posting is not allowed, and does not make it any more relevant...sounds more like they were experimenting than testing...

That's nice. In January, Chinese authorities had already ordered the Wuhan COVID19 virus samples destroyed, worked to muzzle concerned Wuhan M.D.s, and censored public concerns posted online. This is a timeline the world must absolutely scrutinize.

/Go, set a Watchman

Ever watched Silkwood or read Silent Spring?

Here's wondering if you have a point...

/MalariaSurvivor™

Career Politicians are/have liquidated their stocks before the markets ‘crashed’.

the opposite but on the same lines of investing $1,000.00 in cattle futures and quickly turning into $100,000.00

And I’m sure when this coronavirus is brought under control, there will be yet other politicians ‘cashing in’.

yet there are people that don’t care about that, are instead doing this...

fortunately, SE appears to be the only one on topic, with good research and postings keeping us updated.

Politicians are not the only ones to have changed their positions in the market. They do make attractive targets for criticism however. You can be sure there were a lot of people who saw this coming before the market started seriously tanking.

But the same thing applies with market timing. If they are a little slow to get back in the market, they can lose out on the rebound. And the market can move up just as fast as it falls. It is always irrational in the short term.

Over a month ago, I pondered selling some off but I made a conscious decision to let the market ride. It will come back. I do have some cash that's been on the sidelines for over a year now, and I am holding off for now, but when I think the market is low enough, I'm investing that back in. I have not changed a penny of my current holdings. I'm at least five years away from retirement, so there's still plenty of time.

"Social Distancing" is now (slowly) being considered as the wrong terminology. It seems that people need the live interaction so the expression (recommendation?) is shifting to "Physical Separation" so people can to still mingle but stay several feet (six at the grocery this morning) apart.

TBC

You’re correct, when it dwells into bias (On both sides) political pollution, it takes away from the actual point of the matter.

thank you for the course correction and good questions on point.

I don't think there is any side effects associated with that low of a dose, tonic water has more...Basically what we are waiting for is FDA approval, they are running clinical trials as we speak, and have approved it for the most severe cases, but not for prophylactic purposes or regular treatment yet...A safe and effective dose must be determined through clinical trials before approval can be issued under FDA rules, though I suspect some streamlining may be possible with good clinical results early on....also to be determined is the most effective form of the drug, which seems to be

Hydroxychloroquine....

..."This week, some of those same researchers published research in Cell Discovery comparing chloroquine and hydroxychloroquine, showing chloroquine was more active than hydroxychloroquine, but the lower toxicity of hydroxychloroquine could allow it to be dosed at a higher level and make up for the lower activity. The anti-inflammatory property of hydroxychloroquine could also make the drug more effective since some patients with COVID-19 have had overactive immune systems that result in a cytokine storm where the immune system starts attacking the patient's own cells."...

Thanks,

Clinical trials to determine dosage and such for this already registered medication would significantly reduce the lead time for implementation (Relative to a new developed drug or vaccine) since they would only be researching to determine "effective dosage" and provided that is below what has already received approval would receive registration relatively simply.

If it is effective, then what level of community take-up is necessary? I saw the virus has a 2.2 infection ratio, so how do we get that to be similar to measles or chicken pox in the general immunised community where the background infections are "nuisance" to the health system rather than the current apparent tsunami that has everyone concerned.

It seems to me that anybody that tests positive for the virus should be given hydroxychloroquine together with a zinc supplement...I am taking zinc supplement and drinking a tonic water with quinine every few days as a preventative measure...the poor man's cure....don't know if it works...but it doesn't hurt ....haha

I had heard on the radio yesterday, if you are suspect of having the CV, and you make an appointment to get tested, from that time on you are automatic counted as a CV case, unless or until the tests come back negative.

so the counts may be larger, but it’s a conservative way of counting. Which is ok, better being wrong that a carrier.

There's too many that are asymptomatic to get an accurate count, that's why isolation is the only control method that can work....We should be able to determine the actual number of infected by the number of deaths, assuming a ~1% death rate it's a 20 day lagging indicator...don't know how valuable that information will be, but it should tell the amount that were asymptomatic....

There are a few potential issues with hydroxychloroquine. Patients should be monitored closely. (see below from here)

For Healthcare Professionals

Applies to hydroxychloroquine: compounding powder, oral tablet

Cardiovascular

Frequency not reported: Cardiomyopathy (can result in fatal cardiac failure), biventricular hypertrophy[Ref]

Dermatologic

Common (1% to 10%): Rash, pruritus

Uncommon (0.1% to 1%): Pigmentary changes in skin and mucous membranes, bleaching of hair, alopecia

Frequency not reported: Urticaria, angioedema, bullous eruptions including erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis, Drug Rash with Eosinophilia and Systemic Symptoms (DRESS syndrome) photosensitivity, exfoliative dermatitis, acute generalized exanthematous pustulosis (AGEP)[Ref]

-Pigmentary changes in skin and mucous membranes, bleaching of hair, and alopecia are usually reversible when therapy is discontinued.

-AGEP should be distinguished from psoriasis, although this drug may precipitate attacks of psoriasis; it may be associated with fever and hyperleukocytosis[Ref]

Gastrointestinal

Very common (10% or more): Abdominal pain, nausea

Common (1% to 10%): Diarrhea, vomiting[Ref]

Hematologic

Frequency not reported: Bone-marrow depression, anemia, aplastic anemia, agranulocytosis, leucopenia, thrombocytopenia[Ref]

Hepatic

Uncommon (0.1% to 1%): Abnormal liver function tests

Frequency not reported: Fulminant hepatic failure[Ref]

Hypersensitivity

Frequency not reported: Allergic reactions (urticaria, angioedema, bronchospasm), hypersensitivity myocarditis[Ref]

Metabolic

Common (1% to 10%): Anorexia

Frequency not reported: Hypoglycemia, exacerbation or precipitation of porphyria[Ref]

Musculoskeletal

Myopathy may be reversible after therapy discontinuation, but recovery may take many months.[Ref]

Uncommon (0.1% to 1%): Sensorimotor disorders

Frequency not reported: Skeletal muscle myopathy or neuromyopathy (leading to progressive weakness and atrophy of proximal muscle groups), depression of tendon reflexes and abnormal nerve conduction studies[Ref]

Nervous system

Very common (10% or more): Headache

Uncommon (0.1% to 1%): Dizziness

Frequency not reported: Seizure, vertigo, nerve deafness, ataxia[Ref]

Ocular

-Blurring of vision is due to a disturbance of accommodation which is dose dependent and reversible.

-Retinopathy is uncommon if the recommended daily dose is not exceeded. It is usually reversible if therapy is discontinued. If allowed to develop, there may be a risk of progression even after treatment withdrawal.

-Patients with retinal changes may be asymptomatic initially, or may have scotomatous vision with paracentral, pericentral ring types, temporal scotomas, and abnormal color vision.

-Corneal changes including edema and opacities can be symptomless or may cause disturbances such as haloes, blurring of vision or photophobia. They may be transient and are reversible when therapy is discontinued.

-Maculopathies and macular degeneration can occur from 3 months to several years of exposure to this drug and may be irreversible.[Ref]

Common (1% to 10%): Blurred vision

Uncommon (0.1% to 1%): Retinopathy (with changes in pigmentation and visual field defects), corneal changes haloes (e.g., blurring of vision, photophobia)

Frequency not reported: Maculopathies and macular degeneration (may be irreversible), extra-ocular muscle palsies (reversible), nystagmus[Ref]

Other

Uncommon (0.1% to 1%): Tinnitus

Frequency not reported: Hearing loss[Ref]

Psychiatric

Common (1% to 10%): Affect liability

Uncommon (0.1% to 1%): Nervousness

Frequency not reported: Psychosis, suicidal behavior[Ref]

Respiratory

Frequency not reported: Bronchospasm[Ref]

References

1. "Product Information. Hydroxychloroquine Sulfate (hydroxychloroquine)." Prasco Laboratories, Cincinnati, OH.

2. "Product Information. Plaquenil (R). (hydroxychloroquine)." Sanofi Winthrop Pharmaceuticals, New York, NY.

3. Cerner Multum, Inc. "Australian Product Information." O 0

4. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

This video is from March 10th (incl. info about chloroquine)

.
And the most recent one from the same channel

Yeah we know...

https://cr4.globalspec.com/thread/133852/Possible-Treatment-For-Corona-Virus

Other diseases are available.

...which represents an egg-cup full per day...

Yeah a shot glass...

With a ginger ale chaser...

That’s about an egg-cup-full per day...

The tonic water has enough then,mg vs mcg.

Now,combine with zinc lozenges...hmmm?

If one were to use quinine water, how much (and/or how often) should one drink it? Certainly not a whole bottle each day as that would be some 138 times the recommended dosage (83/.6). Also, when one does drink it, should one flush down a zinc tablet at the same time? Just trying to think in pro-active terms.

TBC

Caution: Zinc can cause headaches. I get one if I take more than 1 lozenge per day.

Zinc has a rather high toxicity at just 40 - 50 mg....the dosage in supplements is generally 14 mg...I wouldn't exceed that amount you risk damaging your liver...

The WHO will discount the findings.

I imagine this will be how their response will look: "If it works we must disqualify the results as this may color the WHO in a bad light due to our continuing process of providing the world with misinformation. And please stop wearing masks and sanitizing your groceries."

Well, I glad my hydroxychloroquine order didn't get through.

Now I am going to just inject common household disinfectant. It's a hang of a lot cheaper.

Sounds like you’re the type of person that reads ‘Occupy Democrats’ and uses it as references and yells “WE’RE ALL GONNA DIE, SOMEBODY SHOULD DO SOMETHING”