While there may be the occasional genuine situation, I have yet to find one.
If you do decide to reply, be very careful to use a different email address, (Suggest gmail or Hotmail - use fake name when registering for the email account), and do not share your personal information = Name, Address, Phone number, Birthdate, Bank Account Number etc.
Many of those advertisements are used for "Identity Theft".
'Nuff said....
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"The number of inventions increases faster than the need for them at the time" - SparkY
Some home jobs are legitimate and above board and it is a nice way of getting short lived projects done without a worry about office space and equipment and supplying job opportunities. Data capturing can be set out on home contracts.
Unfortunately the potentially good system is abused by employer and employee.
Therefore be aware that it may be a scam.
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Never do today what you can put of until tomorrow - Student motto