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6 comments
Participant

Join Date: Aug 2009
Posts: 2

pharmaceutical water

10/12/2009 3:15 PM

i need advice on how to assemble a pharmaceutical water plant for local use.it should consist of standard pretreatment,adouble reverse osmosis/edi machine,ozonator,storage tank,andappropriate micron filters

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#1

Re: pharmaceutical water

10/12/2009 3:42 PM

Do you have all the bits, the manual and some tools and duct tape to put it all together?

Seriously thou, you need to provide much, much more information on your application as this question is as broad as asking "how do I build a power station?". How can we possibly advise with so little information given?

Don't forget to mention what country you are in, what size plant you need, etc.

Alternatively get a professional engineering consultancy or water treatment company to design and supply a suitable water treatment plant for you.

Participant

Join Date: Aug 2009
Posts: 2
#4
In reply to #1

Re: pharmaceutical water

10/13/2009 5:07 AM

there are only two large pharmaceutical plants in nigeria hence an abnormally high price.that s why i need advice on a local small scale plant with the following scale

-capacity of about 200lph

-standard pretreatment of carbon filtration,hardness tretment,uvlight,multimedia filtration.

-purification with double reverse osmosis/edi and ozonisation/micron filters .

-storage/continous loop mechanism

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#5
In reply to #4

Re: pharmaceutical water

10/13/2009 12:41 PM

I could tell you how to design one, but for such a low flow as 200lph, it would be much cheaper to google for an off-the-shelf lab system rather than having a custom-built system installed in your plant.

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#2

Re: pharmaceutical water

10/12/2009 4:12 PM

Start here:

Search GlobalSpec

Type in: "water treatment equipment" and get some ideas.

"Alternatively get a professional engineering consultancy or water treatment company to design and supply a suitable water treatment plant for you."

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Power-User

Join Date: Jan 2008
Location: Durban, South Africa
Posts: 374
Good Answers: 7
#3

Re: pharmaceutical water

10/13/2009 3:42 AM

Such a complicated way of doing a simple thing. Just distill it - you can do this several times just to make sure that it is as pure as you can get it. Do not distill to dryness - chuck the last bit away it will contain the impurities

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Join Date: May 2008
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#6

Re: pharmaceutical water

10/13/2009 3:19 PM

olatunde,

What grade of Pharmaceutical water are you interested in? i.e Purified Water (PW), Water for Injection (WFI) etc. You mention double reverse osmosis treatment so it could possibly be WFI that you are intesested in. You should note that this method of producing WFI is not acceptable in the European Pharmacopoeia, therefore you would have to distill. However this may not be of concern to you. Double pass RO is an acceptable method of WFI production in the US and Japan (I think). Japan also allows ultra filtration. Generally, Pharmaceutical companies tend to follow the above three regulatory bodies as this is where most profit comes from, however as I said above this may not be of concern to you.

Before you can begin this project you will need to get data from the supply water as this will have an impact on the pretreatment, for example is the water hard, typical TOC levels, silica etc - this is in response to your "standard pretreatment" comment.

It is not good practice to install filters on the water loop, if indeed that is your intention. Perhaps you could install UV lamps 185nm & 254nm (say one for micro control and one to destruct the O3 (if O3 residue is an issue)).

Google Theodore H. Meltzer and purchase one of his books on the subject.

The volume that you require is quite low so perhaps you maybe able to purchase an off the shelf unit that meets your requirements. In either case it is most probable that you will have to qualify/ validate the system if you are in the pharmaceutical industry.

Kind Regards

Mr. W.A Snow

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DVader1000 (1), hazman (1), HoleInTheSnow (1), jack of all trades (1), lynlynch (1), olatunde (1)

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