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Looking for the Stimulus Pattern for Prosthesis

10/04/2012 5:01 AM

Hi all,I am doing my post graduation project in biomedical electronics.I 've to construct a prosthetic device which replaces 'hippocampus' in the brain region which does the function of 'Delayed-Non Match sample' and thereby helps in formation of new memories.If possible, please lemme know the wave pattern for the inputs to be given for stimulation and also brief me on space-time distribution of neurons.
Thanks in advance

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#1

Re: Looking For the Stimulus Pattern For prosthesis1

10/04/2012 6:10 AM

Way, way way out of my (and probably everyone else here's) field of expertise.
Good luck
Del

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#2

Re: Looking for the Stimulus Pattern for Prosthesis

10/04/2012 11:54 AM

I don't know but if you are starting from scratch you might do some Googling on EEG. A few months ago I did a little (very little) EEG research and found signal levels and impedances for both surface contacts and sub-skin probe needles. The Google hits included frequency information for various parts of the brain and various mental functions. This isn't exactly what you want but it MIGHT get you within an order of magnitude on your signals and might give you references to the more detailed information that you need.

Bruce

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#5
In reply to #2

Re: Looking for the Stimulus Pattern for Prosthesis

10/05/2012 5:38 AM

Thanks a lot Could u please brief me how to overcome the limitation of space-time distribution of neurons.

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Guru

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#3

Re: Looking for the Stimulus Pattern for Prosthesis

10/05/2012 4:22 AM

Have you tried contacting the National Institute of Mental Heath and Neuro Sciences (NIMHANS) in Bangalore? They do have some research programmes running. They have programmes associated with dementia, epilepsy and other neurological conditions that have a bearing on short and long term memory.

Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, which is an Institute of national importance, also has many active research porgrammes. The institute has a major biomedical technology wing as well. You can contact them also.

http://www.sctimst.ac.in/Academic%20and%20Research/Research/Research%20Areas/

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#4
In reply to #3

Re: Looking for the Stimulus Pattern for Prosthesis

10/05/2012 5:27 AM

Thanks a lot.I'll try doing that

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Guru

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#6

Re: Looking for the Stimulus Pattern for Prosthesis

10/08/2012 10:20 PM

This article scratches the surface (if you are new to brainwave magnitude and timing) science), as does this one. As far as I know, (and it has been many decades since I stuck probes into rat brains) the mechanisms of the hippocampus are not well-understood: we can say what happens when is is missing or damaged, but not how to fix it.

Sounds like a really fascinating and extremely valuable project. I hope you and others progress quickly enough that when I start sliding into Alzheimer's, there will be a fix.

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#7

Re: Looking for the Stimulus Pattern for Prosthesis

10/31/2012 2:40 PM

You need to use the relevant terminology for this research. A search for "wave pattern" will probably land you back in the sixties.

Neural prosthetics of the present generation use "stimulus pulse trains", and in general are designed to have variable parameters which may include waveform, pulse duration, pulse rate, and amplitude, as well as duration of on/off cycles, etc. EEG terms (alpha, beta waves etc) are not used to describe these parameters.

You can access reports of the ongoing 'cutting edge' research at NINDS Neural Interfaces Program and Neural Interfaces Workshops here:

http://www.ninds.nih.gov/research/npp/index.htm

Then again, you may just want to read the article that describes your specific project, involving the 'DNMS' model, just published July 2012. Apparently, a biomimetic MIMO approach worked.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395724/

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